Dr Chung King Lueh's MSc Aesthetic Medicine & MSc Dermatology Course Overview & Case Studies
基底細胞皮膚癌
🩺 Case Study: Basal Cell Carcinoma of the Neck in a 65-Year-Old Female
Patient Presentation
A 65-year-old female presented with a solitary skin lump located on the left upper neck. The lesion measured approximately 1 cm × 1 cm and had been gradually enlarging over several months. She reported no pain or bleeding, but noted occasional crusting and a pearly appearance.
Clinical Suspicion: Basal Cell Carcinoma
Basal Cell Carcinoma (BCC) is the most common form of skin cancer, typically arising in sun-exposed areas. In this case, the lesion’s location on the neck and its clinical features raised suspicion for BCC. Key signs and symptoms include:
Pearly or translucent nodule with rolled edges
Central ulceration or crusting
Telangiectasia (visible small blood vessels)
Slow but progressive growth
Non-healing wound or sore
Although BCC rarely metastasizes, it can cause significant local tissue destruction if left untreated.
Surgical Approach
Given the lesion’s size and location, a complete excision under local anesthesia was performed. The surgical margins were carefully planned to ensure complete removal while preserving cosmetic appearance and minimizing functional impact. The procedure involved:
Elliptical excision with a margin of clinically normal skin
Hemostasis and layered closure to optimize healing
Specimen labeling and documentation
Histological Examination
The excised tissue was sent for histopathological analysis to confirm the diagnosis and assess margin clearance. Histology typically reveals:
Basaloid cells forming nests or cords
Peripheral palisading of nuclei
Stromal retraction around tumor islands
Confirmation of BCC and clear margins would indicate successful treatment. If margins are involved, further excision or alternative therapy may be considered.
Conclusion
Early recognition and prompt excision of suspicious skin lesions are critical in managing BCC. In this case, the patient underwent a safe and effective procedure with tissue sent for histological confirmation. Ongoing follow-up is essential to monitor for recurrence or new lesions.
🩺 病例報告:65歲女性頸部基底細胞癌
病人概況
一名65歲女性因左上頸部出現皮膚腫塊前來求診。該病灶大小約為1公分 × 1公分,過去數月逐漸增大。病人未訴疼痛或出血,但偶爾有結痂現象,外觀呈現珍珠狀。
臨床懷疑:基底細胞癌
基底細胞癌(Basal Cell Carcinoma, BCC)是最常見的皮膚癌,常發生於長期曝曬的部位。此病灶位於頸部,且具備典型臨床特徵,因此高度懷疑為BCC。常見症狀包括:
珍珠狀或半透明結節,邊緣隆起
中央潰瘍或結痂
表面可見擴張微血管(毛細血管擴張)
緩慢但持續增大
不癒合的傷口或潰瘍
雖然BCC極少轉移,但若未及時治療,可能造成局部組織破壞。
手術處理
考量病灶大小與位置,安排在局部麻醉下進行完整切除手術。手術計劃以確保完全切除病灶為原則,同時兼顧美觀與功能。手術步驟包括:
橢圓形切除,保留適當安全邊界
止血與分層縫合,促進傷口癒合
標記並送檢切除組織
組織病理檢查
切除組織送至病理科進行組織學檢查,以確認診斷並評估切緣是否清除乾淨。典型病理表現包括:
基底樣細胞形成細胞巢或索狀排列
細胞核排列呈柵欄狀(周邊排列)
腫瘤細胞周圍基質收縮現象
若病理報告確認為BCC且切緣清潔,則表示治療成功。若切緣受侵犯,則需考慮再次切除或其他治療方式。
結語
對可疑皮膚病灶的早期辨識與及時切除,是治療基底細胞癌的關鍵。本案例中,病人接受安全有效的手術,並將組織送檢以確認診斷。後續仍需定期追蹤,以監測是否有復發或新病灶出現。